List of missable content (XC1)

Xenoblade Chronicles has a significant amount of missable content. Most of this is because the game has several areas that cannot be revisited past certain points in the story, but there are also many s that have a choice of which branch to complete, or that are mutually-exclusive with each other.

While the Definitive Edition does not technically add any missable content, equipment appearances are missable in the same way that equipment itself is.

Unrevisitable areas
Once an area becomes unrevisitable, everything within it can no longer be accessed. This includes s, enemies (most importantly s), ether crystal deposits, and any, s, and s that they would provide. Any quests that require being in the area will expire. Collectables will be available in Colony 6 as it is reconstructed, though this makes them very tedious to obtain.


 * The Ether Mine can be entered, but the Central Pit is blocked off after Xord is defeated, making about half the area inaccessible. There is nothing particularly important within aside from crystal deposits, and all its locations and landmarks are mandatory and thus unmissable.
 * All areas of Mechonis, except for the Fallen Arm, become unavailable at various points.
 * Sword Valley and Galahad Fortress cannot be entered once the allied force invades.
 * Mechonis Field cannot be entered after defeating in Agniratha.
 * Central Factory and Agniratha cannot be skip travelled into after defeating Yaldabaoth in Agniratha. However, upon re-entering the Mechonis, the party finds themselves in the Central Factory and can travel anywhere within it on foot, and from there also freely access Agniratha. After escaping Mechonis Core, both (in addition to the Core itself) become entirely inaccessible.
 * Prison Island cannot be skip travelled into after the events of Mechonis Core. It is later re-entered as part of the story, but as an entirely separate map that must be re-discovered.

In addition to the above, Alcamoth cannot be skip travelled into after the events of Mechonis Core, and all its NPCs either move elsewhere or are no longer present. It can only be re-entered on foot, and quests must be done to re-unlock certain areas.

Expirable quests
Many quests are marked with a clock icon to show that they can expire at some point - either because of a story event, or because another quest is completed first and the two are mutually exclusive.

Missable events
Most NPC dialogue is fluff text that is technically missable but of little importance. However, certain ones are actually important.
 * Talking to Kallian as Melia after reaching the Pod Landing Site will have her obtain the Imperial Staff. Once Kallian leaves with the allied force, the opportunity to get the weapon (and its unique appearance) is lost.
 * Talking to Shulk as Melia immediately after escaping Mechonis Core and landing in Colony 6 leads to a unique interaction.

Mutually-exclusive invitations
Certain NPCs can be invited to Colony 6. However, some can only be invited if someone else has not been invited first. Who to choose greatly affects which interactions and quests later become available.